BioResearchAgent

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Task F1 · contradiction handling

Is the finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected a settled consensus in the corpus, or is it contested/being re-evaluated?

Gold evidence

Acceptable answer concepts

  • the abstract explicitly re-evaluates a prior study's finding
  • framed as uncertain / under re-analysis, not settled consensus
  • should not be reported as unqualified consensus

Construction note

PMID:42642214 opens by calling the prior result 'uncertain' and describes re-evaluating it on an independent cohort to reduce ascertainment/survivor bias -- a genuine in-corpus evidentiary tension, not a fabricated contradiction.

How each architecture answered

Baseline 0 · no retrieval

Yuu no Sekai · 533 tokens · 3.4s

(abstained) The provided query cannot be answered as no evidence passages were retrieved for this question.

hypothesisverifiedconf 0.50

The finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected is a settled consensus in the corpus.

hypothesisverifiedconf 0.50

The finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected is contested or being re-evaluated.

run_failed: 0abstention_correct: 0%concept_coverage: 0%

Baseline 1 · retrieve + synthesize

Yuu no Sekai · 2816 tokens · 7.2s
query(ies): Is the finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected a settled consensus in the corpus, or is it contested/being re-evaluated?

The finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected is not a settled consensus but rather a finding supported by recent studies. The evidence suggests that the risk remains uncertain, with some studies indicating lower-than-expected incidence in the first decade following an ovarian cancer diagnosis.

factualverifiedconf 0.95

Breast cancer risk after ovarian cancer in germline BRCA1/2 carriers remains uncertain.

PMID:42642214Direct support
factualverifiedconf 0.90

A recent study reported lower-than-expected incidence of breast cancer in the first decade after ovarian cancer diagnosis in BRCA1/2 carriers.

PMID:42642214Direct support
relationverifiedconf 0.85

The lower incidence of breast cancer after ovarian cancer is supported by the findings of a refined cohort study.

PMID:42642214Direct support
comparisonverifiedconf 0.80

There is no agreement or consensus on this finding in the literature.

PMID:42642214Direct support
run_failed: 0retrieval_recall_at_k: 100%retrieval_mrr: 100%claim_support_rate: 100%unsupported_claim_rate: 0%citation_precision: 100%source_validity_rate: 100%abstention_correct: 100%concept_coverage: 0%

Agent 1 · planner + retrieve + synthesize

Yuu no Sekai · 3459 tokens · 8.3s
query(ies): breast cancer risk after ovarian cancer germline BRCA1/2 carriers consensus | breast cancer risk after ovarian cancer germline BRCA1/2 carriers contested | breast cancer risk after ovarian cancer germline BRCA1/2 carriers re-evaluation
planner → {"queries": ["breast cancer risk after ovarian cancer germline BRCA1/2 carriers consensus", "breast cancer risk after ovarian cancer germline BRCA1/2 carriers contested", "breast cancer risk after ovarian cancer germline BRCA1/2 carriers re-evaluation"]}

The finding that breast-cancer risk after ovarian cancer in germline BRCA1/2 carriers is lower than expected is not a settled consensus but rather a finding that remains uncertain and under re-evaluation.

factualverifiedconf 0.95

Breast cancer risk after ovarian cancer in germline BRCA1/2 heterozygotes remains uncertain with recent studies reporting lower-than-expected incidence in the first decade.

PMID:42642214Direct support
comparisonverifiedconf 0.85

Incidence of breast cancer after ovarian cancer was lowest within the first 5 years and increased beyond 10 years, aligning with findings from Apostol et al.

PMID:42642214Direct support
hypothesisverifiedconf 0.75

There is ongoing re-evaluation of breast cancer incidence after ovarian cancer in BRCA1/2 carriers.

PMID:42642214Direct support
run_failed: 0retrieval_recall_at_k: 100%retrieval_mrr: 100%claim_support_rate: 100%unsupported_claim_rate: 0%citation_precision: 100%source_validity_rate: 100%abstention_correct: 100%concept_coverage: 33%