BioResearchAgent

← all tasks

Task G2 · insufficient evidence

Does the corpus provide evidence that EGFR regulates TP53-mutation-driven immune suppression?

Gold evidence

None — this is a deliberate “insufficient evidence” trap. The correct behavior is abstention.

Acceptable answer concepts

  • insufficient evidence
  • EGFR only co-occurs with P53 as an immunohistochemical marker in an unrelated diagnostic study

Construction note

EGFR appears only in PMID:42703120, a diagnostic-marker study (cyclin D1/EGFR/P53/Ki-67 in epithelial dysplasia) with no regulatory or mechanistic claim about immune suppression. This is the 'plausible-sounding false association' trap task (see spec section 18).

How each architecture answered

Baseline 0 · no retrieval

Yuu no Sekai · 417 tokens · 2.5s

(abstained) No evidence was retrieved to answer the question.

abstentionverifiedconf 0.00

The corpus provides evidence that EGFR regulates TP53-mutation-driven immune suppression.

run_failed: 0abstention_correct: 100%concept_coverage: 0%

Baseline 1 · retrieve + synthesize

Yuu no Sekai · 2504 tokens · 3.2s
query(ies): Does the corpus provide evidence that EGFR regulates TP53-mutation-driven immune suppression?
PMID:42700791PMID:42575068PMID:31792264PMID:42656272PMID:42701058

(abstained) The provided corpus does not contain evidence that EGFR regulates TP53-mutation-driven immune suppression.

hypothesisverifiedconf 0.00

EGFR regulates TP53-mutation-driven immune suppression

run_failed: 0retrieval_recall_at_k: 100%retrieval_mrr: 0%abstention_correct: 100%concept_coverage: 0%

Agent 1 · planner + retrieve + synthesize

Yuu no Sekai · 2962 tokens · 5.1s
query(ies): EGFR TP53 mutation immune suppression | EGFR regulation of TP53-mutated immune suppression | EGFR role in TP53-driven immune suppression
PMID:42700791PMID:42656272PMID:42698831PMID:31792264PMID:42701058
planner → {"queries": ["EGFR TP53 mutation immune suppression", "EGFR regulation of TP53-mutated immune suppression", "EGFR role in TP53-driven immune suppression"]}

(abstained) The provided corpus does not contain evidence that EGFR regulates TP53-mutation-driven immune suppression.

hypothesisverifiedconf 0.00

EGFR regulates TP53-mutation-driven immune suppression

run_failed: 0retrieval_recall_at_k: 100%retrieval_mrr: 0%abstention_correct: 100%concept_coverage: 0%